Revista Brasileira de Anestesiologia
On-line version ISSN 1806-907X
KRAYCHETE, Durval Campos; GUIMARAES, Ana Cristina; CARVALHO, Maria Goreth and CARVALHO, Edgar Marcelino de. Intravenous lidocaine to treat scleroderma pain: case report. Rev. Bras. Anestesiol. [online]. 2003, vol.53, n.6, pp. 797-801. ISSN 1806-907X. http://dx.doi.org/10.1590/S0034-70942003000600010.
BACKGROUND AND OBJECTIVES: Scleroderma or progressive systemic sclerosis is a systemic connective tissue disease of unknown origin, which normally courses with microangiopathy, extremities ischemia and severe pain. This report aimed at describing a case of intravenous lidocaine to treat ischemic pain and at emphasizing potential anti-inflammatory action of local anesthetics in scleroderma patients. CASE REPORT: Female patient, clear mulatto 34 years old, nursing assistant, with scleroderma for approximately 8 years, presented with severe continuous, daily pain (numeric scale = 10) in upper and lower limbs, followed by trophic, color and temperature changes, and small ulcers on extremities. Patient was submitted to 1 weekly session of intravenous 2% lidocaine (400 mg) without vasoconstrictor for 10 weeks with pain, turgor, skin elasticity and peripheral perfusion improvement. CONCLUSIONS: Pain and other symptoms relief after intravenous lidocaine suggests that local anesthetics are able to modulate inflammatory response in different scleroderma stages.
Keywords : ANESTHETICS [Local]; ANESTHETICS [lidocaine]; DISEASES [scleroderma]; PAIN [Chronic].