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Revista Brasileira de Anestesiologia

Print version ISSN 0034-7094On-line version ISSN 1806-907X


NUNES, Rogean Rodrigues; ALMEIDA, Murilo Pereira de  and  SLEIGH, James Wallace. Spectral entropy: a new method for anesthetic adequacy. Rev. Bras. Anestesiol. [online]. 2004, vol.54, n.3, pp.404-422. ISSN 0034-7094.

BACKGROUND AND OBJECTIVES: Though universally employed, clinical signs to evaluate anesthetic adequacy are not reliable. Over the past years several pieces of equipment have been devised to improve intraoperative handling of anesthetic drugs, some of them directly measuring cerebral cortical activity (hypnosis). None of them, however, has offered the possibility of directly evaluating sub-cortical activity (motor response). CONTENTS: Spectral entropy measures irregularity, complexity or amount of EEG disorders and has been proposed as indicator of anesthetic depth. Signal is collected from the fronto-temporal region and processed according to Shannon's equation (H = - Spk log pk, where pk represents the probability of a discrete k event), resulting in two types of analyses: 1) state entropy (SE), which evaluates cerebral cortex electrical activity (0.8 - 32Hz) and 2) response entropy (RE), containing both subcortical electromyographic and cortical electroence- phalographic components and analyzes frequencies in the range 0.8 - 47Hz. CONCLUSIONS: Frontal muscles activation may indicate inadequacy of the subcortical component (nociception). Such activation appears as a gap between SE and RE. This, it is possible to directly evaluate both cortical (SE) and subcortical (RE) components providing better anesthetic adequacy.

Keywords : MONITORING [bispectral index]; MONITORING [state entropy]; MONITORING [response entropy].

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