SciELO - Scientific Electronic Library Online

 
vol.55 issue4Methadone to treat non-oncologic neuropathic pain: case reportsStrictu sensu post-graduation in anesthesiology: experience of ten years at Universidade Estadual Paulista author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Revista Brasileira de Anestesiologia

On-line version ISSN 1806-907X

Abstract

LUFT, Ana  and  MENDES, Florentino Fernandes. Low S(+) ketamine doses: a review. Rev. Bras. Anestesiol. [online]. 2005, vol.55, n.4, pp. 460-469. ISSN 1806-907X.  http://dx.doi.org/10.1590/S0034-70942005000400011.

BACKGROUND AND OBJECTIVES: Low doses of ketamine or isomers are promising possibilities for anesthesia and postoperative analgesia. This study aimed at reviewing major properties of low ketamine doses, which may justify their use in anesthesia and postoperative analgesia. CONTENTS: Literature suggests that ketamine induces preemptive and preventive postoperative pain relief, decreasing opioid consumption and improving patients' satisfaction. Opioid-induced tolerance and hyperalgesia may be minimized with low ketamine doses. Ketamine decreases inhalational anesthetic consumption and may protect ischemic nervous cells. Promising effects, such as neuroprotection and improvement of long-term outcomes, require further studies. CONCLUSIONS: Most studies with low S(+) ketamine doses have shown preventive effects, decreasing central nervous system sensitization, opioid-induced tolerance and hyperalgesia, anesthetic and analgesic consumption, and the incidence of postoperative adverse effects.

Keywords : ANESTHETICS [ketamine]; COMPLICATIONS [Postoperative]; PAIN [Treatment].

        · abstract in Portuguese | Spanish     · text in English | Portuguese     · English ( pdf epdf ) | Portuguese ( pdf epdf )

 

Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License