SciELO - Scientific Electronic Library Online

vol.58 issue4Thoracic epidural block performed safely in anesthetized patients: a study of a series of casesLocal effect of tramadol on formalin evoked flinching behavior in rats author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




Related links


Revista Brasileira de Anestesiologia

Print version ISSN 0034-7094On-line version ISSN 1806-907X


GEOVANINI, Glaucylara Reis et al. Standardization of anesthesia in swine for experimental cardiovascular surgeries. Rev. Bras. Anestesiol. [online]. 2008, vol.58, n.4, pp.363-370. ISSN 0034-7094.

BACKGROUND AND OBJECTIVES: Although dogs are the animals used more often in Experimental Surgeries, the use of sheep, bovine, and swine as models for scientific experiments has been growing. Thus, further learning on the treatment and basic standardization of more complex surgeries in swine are necessary. The objective of this study was to evaluate sedation and analgesia, obtained by the intramuscular administration of midazolam and ketamine, and local anesthetics with 2% lidocaine without vasoconstrictor, in tracheostomy and dissection of femoral artery and vein. METHODS: The heart rate and corneal-palpebral reflex were evaluated at the beginning of sedation, during the surgical procedures, and at the end of those procedures. Eight Large White swine, without prior treatment, weighing 35 to 42 kg were provided by local farms. They received intramuscular injections of 22 of ketamine and 0.3 of midazolam. RESULTS: The anesthetic approach on those animals, who present both difficult intubation and access to deep vessels, proved to be safe for sedation and analgesia by the method chosen: intramuscular administration. CONCLUSIONS: An adequate plane of anesthesia for the proposed procedure was achieved.

Keywords : ANALGESICS [ketamine]; ANIMALS [pigs]; HYPNOTICS, benzodiazepines [midazolam]; SURGERY [experimental].

        · abstract in Portuguese | Spanish     · text in English | Portuguese     · English ( pdf epdf ) | Portuguese ( pdf epdf )


Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License