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Revista Brasileira de Anestesiologia
Print version ISSN 0034-7094
MORAIS, Bruno Salome de et al. Association between the use of blood components and the five-year mortality after liver transplant. Rev. Bras. Anestesiol. [online]. 2011, vol.61, n.3, pp.289-292. ISSN 0034-7094. http://dx.doi.org/10.1590/S0034-70942011000300003.
BACKGROUND AND OBJECTIVES: Liver transplant (LT) surgery is associated with significant bleeding in 20% of cases, and several authors have demonstrated the risks related to blood components. The objective of the present study was to evaluate the impact of using blood components during hospitalization in five-year survival of patients undergoing LT. METHODS: One hundred and thirteen patients were evaluated retrospectively. Several variables, including the use of blood components intraoperatively and throughout hospitalization, were categorized and evaluated by univariate analysis using Fisher's test. A level of significance of 5% was adopted. Results with p < 0.2 underwent multivariate analysis using multinomial logistic regression. RESULTS: Parenchymal diseases, preoperative renal dysfunction, and longer stay in hospital and ICU are associated with greater five-year mortality after LT (p < 0.05). Unlike the intraoperative use of blood components, the accumulated transfusion of packed red blood cell, frozen fresh plasma, and platelets during the entire hospitalization was associated with greater five-year mortality after liver transplantation (p < 0.01). CONCLUSIONS: This study emphasizes the relationship between the use of blood components during hospitalization and increased mortality in five years after LT.
Keywords : Blood Component Transfusion; Liver Transplantation; Fatal Outcome.