Abstract

BARBOSA, Fabiano Timbó  and  CUNHA, Rafael Martins da. Reversal of profound neuromuscular blockade with sugammadex after failure of rapid sequence endotracheal intubation: a case report. Rev. Bras. Anestesiol. [online]. 2012, vol.62, n.2, pp. 283-284. ISSN 0034-7094.  http://dx.doi.org/10.1590/S0034-70942012000200015.

BACKGROUND AND OBJECTIVES: Sugammadex is a reversal agent that acts as a selective antagonist of neuromuscular blockade induced by rocuronium and vecuronium. This is a case report of an elderly female patient who had sugammadex just after rocuronium induction. CASE REPORT: An 88-year-old female patient, 34 kg, presented a femoral fracture and had to undergo general anesthesia after spinal anesthesia failure. Induction was performed with propofol 1.5 mg.kg^-1, rocuronium 1.2 mg.kg^-1, fentanyl 100 mcg, and lidocaine 2 mg.kg^-1. There was no success in either tracheal intubation or laryngeal mask positioning maneuvers. The use of sugammadex at a dose of 16 mg.kg^-1 was required and respiratory function returned to normal. CONCLUSION: Literature recommends sugammadex at a dose of 16 mg.kg^-1 for patients with profound blockade. It was used in our patient with rapid and effective reversal of neuromuscular blockade allowing the patient to undergo another procedure to ensure the airway patency without clinical impairment of her general condition.

Keywords : Intraoperative Complications; Intubation [Intratracheal]; Cyclodextrin [Sugammadex].