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Revista Brasileira de Anestesiologia
Print version ISSN 0034-7094
NIGRO NETO, Caetano; TARDELLI, Maria Angela and PAULISTA, Paulo Henrique Dagola. Use of volatile anesthetics in extracorporeal circulation. Rev. Bras. Anestesiol. [online]. 2012, vol.62, n.3, pp. 350-355. ISSN 0034-7094. http://dx.doi.org/10.1590/S0034-70942012000300007.
BACKGROUND AND OBJECTIVES: The use of volatile anesthetics in cardiac surgery is not recent. Since the introduction of halothane in clinical practice, several cardiac surgery centers started to use these anesthetics constantly. CONTENT: In the last years a great number of studies haveshown that the volatile anesthetics have a protecting effect against myocardial ischemic dysfunction. Experimental evidences have shown that the halogenated anesthetics have cardioprotective effects that cannot be only explained by coronary flow alterations or by the balance between myocardium available and consumed oxygen. In addition to that, the use of volatile anesthetics during extracorporeal circulation (ECC) in cardiac surgery plays an important role. Recent studies have proven that these agents have cardioprotective properties and produce better results when the volatile anesthetic is used during the whole surgery procedure, including ECC. The use of halogenated anesthetics through calibrated vaporizers adapted to the ECC circuit via oxygenator membranes has become popular. Therefore, the professionals involved such as anesthesiologists and perfusionists should learn specifcs in order to solve possible doubts.
Keywords : anesthetics; volatile; cardiac surgical procedures; extracorporeal circulation; ischemic preconditioning; oxygenators; membrane.