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Revista Brasileira de Anestesiologia

Print version ISSN 0034-7094


KRAYCHETE, Durval Campos  and  SAKATA, Rioko Kimiko. Use and rotation of opioids in chronic non-oncologic pain. Rev. Bras. Anestesiol. [online]. 2012, vol.62, n.4, pp.558-562. ISSN 0034-7094.

BACKGROUND AND OBJECTIVES: Prolonged use of opioids is a possibility for chronic pain treatment. Opioids are effective for virtually all chronic non-cancer pain syndromes, but may cause dependence. The aim of this paper is to review the use and rotation of opioids in chronic non-oncologic pain. CONTENT: The use of potent opioids is controversial and not recommended as first-line drugs due to the possibility of dependence. The following topics are described: tolerance, addiction, risk factors for addiction, rotation or replacement, general administration rules, conversion tables, and tips for prescribing opioids. CONCLUSIONS: Opioids are drugs with proven efficacy for chronic non-oncologic pain, but its prescription should meet certain criteria in order to reduce the incidence of adverse effects and addiction.

Keywords : Chronic Pain; Analgesics, Opioid [adverse effects].

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