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Revista Brasileira de Oftalmologia

versão impressa ISSN 0034-7280versão On-line ISSN 1982-8551

Resumo

ALBUQUERQUE, Gabriela Caroline Monteiro de et al. Periorbital presentation of IgG4 related disease. Rev. bras.oftalmol. [online]. 2018, vol.77, n.5, pp.286-288. ISSN 0034-7280.  http://dx.doi.org/10.5935/0034-7280.20180062.

IgG4-Related Disease is an immunomediated condition that is characterized by the presence of inflammatory lesions associated with fibrosis and lymphoplasmacytic infiltration rich in positive IgG4 tissue plasmocytes, forming a spectrum of fibroproliferative diseases. The pathogenesis of IgG4-RD is still poorly understood and the treatment is empirical. We report the case of a 50-year-old man with yellow eyelid lesions associated with local edema, previously diagnosed as an allergic process, until biopsy with immunohistochemical study and serum IgG4 dosage revealed the hypothesis of IgG4 related disease. Treatment with corticoid and rituximab was initiated, showing stabilization of the condition, without presenting other clinical forms of the disease.

Palavras-chave : Immunoglobulin G; Autoimmunity; Eye Manifestations; Fibrosis; Case reports.

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