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Revista Brasileira de Otorrinolaringologia
Print version ISSN 0034-7299
PINEROLI, José C.A. et al. Auditory central avaliation in Parkinson Disease with BERA and P300. Rev. Bras. Otorrinolaringol. [online]. 2002, vol.68, n.4, pp.462-466. ISSN 0034-7299. http://dx.doi.org/10.1590/S0034-72992002000400003.
Introduction: The Parkinson Disease (PD) is one of the disturbance of movement, that attain elderly people. It promotes the progressive and irreversible loss of cells of black substance (locus niger) from the mesencephalon, as a result it will have a reduction of dopamine production leading the syntomatology of PD. Aim: Analyzing the electrophysiologic tests, able to control the functional integrity of the cerebral ways, in the diagnosis and/or prognosis of patients with PD, once these not-invasive tests of easy management, fast and simple understanding, whom have participation in the management. Study form: Random clinical prospective. Material and method: group of 32 patients with previous diagnosis of PD, undertaken to the evoked potential Bera and P300. Male and female patients, among 44 and 85 years old, time of disease variation from 8 to 21 years old of evolution. Results: The Bera and P 300 values found in the patients with PD will not indicate different limits of normality to the age. Conclusion: it was noticed integrity of auditive ways in patients with PD. Once the latency of P300 rises in a linear form with the age after 45 years, accepting a rise of 1-1,5ms a year1; it was observed integrity in the cerebral ways to reflect the ability of cognitive performance in patients with PD without important dementing compromise.
Keywords : Parkinson disease; event-related potentials; P300; evoked potential; auditory; brain stem.