Revista Brasileira de Otorrinolaringologia
Print version ISSN 0034-7299
FREITAS, Tarsila M. C.; MEDEIROS, Ana Miryam C.; OLIVEIRA, Patrícia T. and LIMA, Kenio Costa. Sjögren's syndrome: literature review and clinical case management. Rev. Bras. Otorrinolaringol. [online]. 2004, vol.70, n.2, pp.283-288. ISSN 0034-7299. http://dx.doi.org/10.1590/S0034-72992004000200023.
Sjögren's syndrome is an autoimmune systemic inflammatory disease characterized by progressive lymphocytic infiltration of several exocrine and non-exocrine organs. It affects primarily the lachrymal and salivary glands causing structural damage and secretory dysfunction of the organs. The production of autoantibodies and polyclonal hypergammaglobuinemia indicate that abnormalities of humoral immunity play a significant role in this pathogenesis and its diagnosis is based upon a combination of several clinical and laboratory findings. The purpose of this report is to present one clinical case of Sjögen's syndrome emphasizing its clinical importance and necessity of the earlier diagnosis to improve the patient's quality of life.
Keywords : Sjögren's syndrome; xerostomia; autoimmunity; saliva.