SciELO - Scientific Electronic Library Online

vol.71 issue2Auditory screening in the elderly: comparison between self-report and audiometryDiabetes mellitus as etiological factor of hearing loss author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




Related links


Revista Brasileira de Otorrinolaringologia

Print version ISSN 0034-7299


ALVARENGA, Kátia de Freitas et al. Cognitive P300 potential in subjects with diabetes mellitus. Rev. Bras. Otorrinolaringol. [online]. 2005, vol.71, n.2, pp.202-207. ISSN 0034-7299.

Diabetes Mellitus may lead to alterations in the eyes, kidneys, cranial nerves, peripheral nerves, ears etc. The cognitive function also seems to be compromised in subjects presented with Diabetes Mellitus, since the cortical and subcortical structures responsible for this function are hindered in some insulin-dependent patients. The cognitive potential P300 has been used as an objective procedure to assess cerebral cognitive functions. AIM: To analyze the sensitivity of P300 cognitive potential for the detection of alterations on the auditory cortex secondary to Diabetes Mellitus. STUDY DESIGN: transversal cohort. MATERIAL AND METHOD: Sixteen diabetic subjects of both genders aged 7 to 71 years, and seventeen non-diabetic individuals at the same age range participated in this study. The evaluation procedures were pure tone audiometry (PTA) and P300 cognitive potential. Glycemia of the group presented with Diabetes was assessed prior to applying P300. RESULTS: No statistically significant difference was shown for PTA results. A statically significant difference was observed between groups when analyzing the latency of P300 component measured in Fz. There was a correlation between glycemia and latency and amplitude of P300. CONCLUSION:The investigation of the cognitive potential of P300 is an important procedure for prevention and early diagnosis of neurological changes in individuals presented with Diabetes Mellitus.

Keywords : diabetes mellitus; hearing loss; event-related potentials; p300; audiometry.

        · abstract in Portuguese     · text in English | Portuguese     · English ( pdf epdf ) | Portuguese ( pdf epdf )


Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License