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Revista de Saúde Pública

versão impressa ISSN 0034-8910versão On-line ISSN 1518-8787

Resumo

SOARES, Bernadette Catalan; PROIETTI, Anna Bárbara de F Carneiro; PROIETTI, Fernando Augusto  e  GIPH (INTERDISCIPLINARY HTLV-I/II RESEARCH GROUP). HTLV-I/II and blood donors: determinants associated with seropositivity in a low risk population. Rev. Saúde Pública [online]. 2003, vol.37, n.4, pp.470-476. ISSN 1518-8787.  https://doi.org/10.1590/S0034-89102003000400012.

OBJECTIVE: Blood donors in Brazil have been routinely screened for HTLV-I/II since 1993. A study was performed to estimate the prevalence of HTLV-I/II infection in a low risk population and to better understand determinants associated with seropositivity. METHODS: HTLV-I/II seropositive (n=135), indeterminate (n=167) and seronegative blood donors (n=116) were enrolled in an open prevalence prospective cohort study. A cross-sectional epidemiological study of positive, indeterminate and seronegative HTLV-I/II subjects was conducted to assess behavioral and environmental risk factors for seropositivity. HTLV-I/II serological status was confirmed using enzyme-linked immunosorbent assay (EIA) and Western blot (WB). RESULTS: The three groups were not homogeneous. HTLV-I/II seropositivity was associated to past blood transfusion and years of schooling, a marker of socioeconomic status, and use of non-intravenous illegal drugs. CONCLUSIONS: The study results reinforce the importance of continuous monitoring and improvement of blood donor selection process.

Palavras-chave : HTLV-I infections [blood]; HTLV-II infections [blood]; Blood donors; Risk factors; Prevalence; Serologic tests; Enzyme-linked immunosorbent assay; Blot; Western.

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