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vol.26 número1Levels of hemolytic complement, total C3 and degree of conversion of native C3 in cardiac and indeterminate form of Chagas' diseaseThe nature of the precipitating specific antibodies of the paracoccidioidomycosis (South American blastomycosis) revealed by counterimmunoelectrophoresis índice de autoresíndice de materiabúsqueda de artículos
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Revista do Instituto de Medicina Tropical de São Paulo

versión On-line ISSN 1678-9946

Resumen

CAMPOS, Carlos Alberto Moreira; CAMPOS, Rubens  y  PEREIRA, Leógenes Horácio. Mastomys natalensis as alternative model in studies on experimental schistosomiasis mansoni. Rev. Inst. Med. trop. S. Paulo [online]. 1984, vol.26, n.1, pp.19-24. ISSN 1678-9946.  https://doi.org/10.1590/S0036-46651984000100004.

It was studied aspects of experimental infection and immunity in a rodent — Mastomys natalensis — infected by the LE strain of Schistosoma mansoni. The results were compared with those from albino mouse, that is an excellent animal for experimental schistosomiasis. The studied parameters showed similar results to those found in the mouse. M. natalensis is highly susceptible to S. mansoni infection, being very useful for biological studies and/or immunity observations about this kind of infection. In addition, the high reproduction rate in captivity, easy handling and unexpensive maintenance in laboratory, suggest that M. natalensis could be used as an alternative experimental model in schistosomiasis mansoni studies.

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