SciELO - Scientific Electronic Library Online

 
vol.33 issue4Pulmonary and radiological studies in 58 paracoccidioidomycosis patientsE.L.I.S.A. in human coccidioidomycosis author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Revista do Instituto de Medicina Tropical de São Paulo

Print version ISSN 0036-4665

Abstract

DEL NEGRO, Gilda M.B. et al. The sensitivity, specificity and efficiency values of some serological tests used in the diagnosis of paracoccidioidomycosis. Rev. Inst. Med. trop. S. Paulo [online]. 1991, vol.33, n.4, pp. 277-280. ISSN 0036-4665.  http://dx.doi.org/10.1590/S0036-46651991000400006.

This work reports on the results of double immunodiffusion (ID), counterimmunoelectrophoresis (CIE), complement fixation (CF) and indirect immunofluorescence (IIF) techniques in the serodiagnosis of paracoccidioidomycosis. The study was undertaken on four groups of individuals: 46 patients with untreated paracoccidioidomycosis, 22 patients with other deep mycoses, 30 with other infectious diseases (tuberculosis and cutaneous leishmaniasis) and 47 blood donors as negative controls. Data were obtained using Paracoccidioides brasiliensis antigens, i.e.,a yeast culture filtrate for ID, CIE and CF, and a yeast cell suspension for IIF. The sensitivity, specificity and efficiency values were measured according to GALEN & GAMBINO8.The gel precipitation tests (ID and CIE) showed the greatest sensitivity (91.3 and 95.6%, respectively), maximum specificity (100%) and the highest efficiency values when compared to the CF and IIF tests.

Keywords : Paracoccidioidomycosis; Paracoccidioides brasiliensis; Serological tests.

        · abstract in Portuguese     · text in English     · pdf in English