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Revista do Instituto de Medicina Tropical de São Paulo

On-line version ISSN 1678-9946


NAKAUCHI, C.M. et al. Antibody to human T-lymphotropic virus in a patient with Guillain-Barré syndrome (case report) . Rev. Inst. Med. trop. S. Paulo [online]. 1991, vol.33, n.4, pp.329-331. ISSN 1678-9946.

Serum sample obtained from a male, 12 year old patient suffering from Guillain-Barré syndrome (GBS) was positive for human T-lymphotropic virus (HTLV-I) antibody by the enzyme-linked immunosorbent assay (ELISA) and the Western Blot analysis (WB). Attempts to isolate enteroviruses (including poliovirus) from faecal material in both tissue culture and suckling mice were unsuccessful; in addition, acute and convalescent paired serum samples did not show any evidence of recent poliovirus infection when tested against the three serotypes. Specific tests for detection of Epstein-Barr virus infection were not performed; however, the Paul-Bunnel test yielded negative results. ELISA for detection of anti-cytomegalovirus IgM was also negative. The concomitant occurrence of either adult T cell leukemia (ATL) or lymphoma was not recorded in this case.

Keywords : HTLV-I; Antibody; Guillain-Barré syndrome.

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