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vol.39 número1REACTIVITY OF ANTI-GP43 ANTIBODIES FROM PARACOCCIDIOIDES BRASILIENSIS ANTISERUM WITH EXTRACTS FROM CUTANEOUS LESIONS OF LOBO'S DISEASE: PRELIMINARY NOTESUBCUTANEOUS PHEOHYPHOMYCOSIS CAUSED BY Phoma cava: REPORT OF A CASE AND REVIEW OF THE LITERATURE índice de autoresíndice de assuntospesquisa de artigos
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Revista do Instituto de Medicina Tropical de São Paulo

versão On-line ISSN 1678-9946

Resumo

PRELIMINARY REPORT OF THE USE ON ADULTS OF A RECOMBINANT YEAST-DERIVED HEPATITIS B VACCINE MANUFACTURED BY INSTITUTO BUTANTAN. Rev. Inst. Med. trop. S. Paulo [online]. 1997, vol.39, n.1, pp.39-42. ISSN 1678-9946.  http://dx.doi.org/10.1590/S0036-46651997000100008.

Three 10 µg doses of the recombinant hepatitis B vaccine, manufactured by Instituto Butantan by original technology, were administered in a adult population, mean age 30 years old, following the 0, 1 and 6 months schedule immunization. The clinical trial was considered satisfactory in terms of immunogenicity (anti-HBs titers between 17.5-29500 IU/l, seroconversion 95.3%) and reactogenicity (no incapacitating side effects)

Palavras-chave : Recombinant hepatitis B vaccine; Clinical trials; Adults.

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