Abstract

LACAZ, Carlos da Silva et al. Paracoccidioides brasiliensis: A MYCOLOGIC AND IMMUNOCHEMICAL STUDY OF TWO STRAINS. Rev. Inst. Med. trop. S. Paulo [online]. 1999, vol.41, n.2, pp. 79-86. ISSN 0036-4665.  http://dx.doi.org/10.1590/S0036-46651999000200004.

The authors conducted a mycologic, immunochemical and molecular biology study on two strains of Paracoccidioides brasiliensis, one of them, called IBIÁ, isolated from soil in the municipality of IBIÁ (Minas Gerais) by Silva-Vergara et al. (l996,1998)^20,21, and the other, BAT, cultivated from a human case of paracoccidioidomycosis in Ribeirão Preto (São Paulo/Brazil) by Freitas da Silva (l996)⁶. Both strains showed cotton-like (M) and yeast-like (Y) forms and were pathogenic for testicularly inoculated guinea pigs, producing granulomatous and/or suppurative orchitis. Immunochemically was demonstrated the presence of gp43 by double immunodiffusion, immunoelectrophoresis and immunoblotting.

Keywords : Paracoccidioides brasiliensis; Paracoccidioidomycosis; Immunochemical study.