Revista do Instituto de Medicina Tropical de São Paulo
versión impresa ISSN 0036-4665
SILVA, Eduardo Sérgio da et al. Visceral leishmaniasis caused by Leishmania (Viannia) braziliensis in a patient infected with human immunodeficiency virus. Rev. Inst. Med. trop. S. Paulo [online]. 2002, vol.44, n.3, pp. 145-149. ISSN 0036-4665. http://dx.doi.org/10.1590/S0036-46652002000300006.
The current article reports the case of a 19-month-old-girl, from the state of Minas Gerais, Brazil, with visceral leishmaniasis, by Leishmania (Viannia) braziliensis, and Human Immunodeficiency Virus (HIV) co-infection. The child's mother and father, aged 22 and 27 years old, respectively, were both HIV positive. The child was admitted to the General Pediatric Center, in Belo Horizonte, presenting high fever, fatigue, weight loss and enlargement of liver and spleen. Indirect immunofluorescent test revealed a titer of 1:320 for Leishmania. Such result was confirmed by the presence of amastigotes in bone marrow aspirate samples and culture of promastigote forms. Parasites were identified as being Leishmania (Viannia) braziliensis through PCR, using a L. braziliensis complex primer and a generic primer, followed by hibridization. Specific leishmaniasis therapy (GlucantimeÒ antimonial) was intravenously administered.
Palabras clave : Visceral leishmaniasis; Leishmania (Viannia) braziliensis; Human immunodeficiency virus; PCR.