We describe a case of white-grain eumycetoma caused by Scedosporium apiospermum in an immunocompetent host that was successfully treated with oral voriconazole, and we review the Brazilian reports on scedosporiosis.
Scedosporium apiospermum ; Pseudallescheria boydii ; Scedosporiosis; Eumycetoma, Voriconazole
| Case (Ref.) | Age/Gender | Diagnostic specimen | Associated diseases | Type of infection | Treatment/Outcome |
|---|---|---|---|---|---|
| 1 (17) | 65/M | Lung tissue | Active tuberculosis | Lung fungus ball | None/Death |
| 2 (3) | 38/M | Soft tissue | None | Mycetoma-like infection | None/Improved |
| 3 (8) | Not done | Lung and brain tissue | Leukemia | Brain and lung abcesses | None/Death |
| 4 (9) | 45/M | Soft tissue | Diabetes and renal transplant recipient | Subcutaneous nodule | Surgical resection and Itraconazole/Cure |
| 5 | 73/F | Soft tissue | Breast carcinoma | Subcutaneous ulcerated lesion | None/death |
| 6 (18) | 66/F | Soft tissue | None | Subcutaneous nodule | Itraconazole/Cure |
| 7 (11) | 40/M | Maxillary sinus tissue | Bone marrow transplantation | Sinusitis | Amphotericin B, itraconazole/Death |
| 8 (19) | 41/F | Lung tissue | Cured tuberculosis, Diabetes | Lung fungus ball | Ketoconazole/Death |
| 9 (20) | 12/M | Peritoneal effusion | End stage renal disease | Peritonitis | None/Improved |
| 10 | 45/M | Lung tissue | Cured tuberculosis | Lung fungus ball | Surgery/Cure |
| 11 | 36/F | Lung tissue | diabetes | Lung fungus ball | Surgery/Cure |
| 12 | 57/F | Lung tissue | Cured tuberculosis | Lung fungus ball | Surgery/Cure |
| 13 (21) | 66/M | Maxillary sinus tissue | None | Maxillary sinus fungus ball | Surgery/Cure |
| 14 (5) | 32/M | Spinal fluid | Near drowning | Central nervous system | Fluconazole, amphotericin B/Death |
| 15 | 58/F | Soft tissue | None | Eumycetoma | Itraconazole, Voriconazole/Cure |
