Iveson (1975)2323. Iveson JM, McDougall AC, Leathem AJ, Harris HJ. Lepromatous
leprosy presenting with polyarthritis, myositis, and immune-complex
glomerulonephritis. Br Med J. 1975;3:619-21.
|
1 |
19 |
M |
Poliarthritis |
Diffuse proliferative lesion |
AKI |
Date (1977)1212. Date A, Thomas A, Mathai R, Johny KV. Glomerular pathology in
leprosy. An electron microscopic study. Am J Trop Med Hyg.
1977;26:266-72.
|
19 |
|
|
Proteinuria |
Diffuse proliferative lesion |
Hematuria |
Amyloidosis |
Singhal (1977)5353. Singhal PC, Chugh KS, Kaur S, Malik AK. Acute renal failure in
leprosy. Int J Lepr Other Mycobact Dis. 1977;45:171-4.
|
3 |
|
|
AKI |
Acute tubular necrosis |
Crescentic nephropathy |
Gupta (1981)2020. Gupta SC, Bajaj AK, Govil DC, Sinha SN, Kumar R. A study of
percutaneous renal biopsy in lepromatous leprosy. Lepr India.
1981;53:179-84.
|
21 |
|
|
|
Diffuse proliferative lesion |
Amyloidosis |
Phadnis (1982)4242. Phadnis MD, Mehta MC, Bharaswadker MS, Kolhatkar MK, Bulakh PN.
Study of renal changes in leprosy. Int J Lepr Other Mycobact Dis.
1982;50:143-7.
|
50 |
|
|
|
Membranoproliferative nephropathy |
Membranous nephropathy |
Amyloidosis |
Chugh (1983)77. Chugh KS, Damie PB, Kaur S, Shama BK, Kumar B, Sakhuja V, et al.
Renal lesions in leprosy amongst north Indian patients. Postgrad Med J.
1983;59:707-11.
|
60 |
|
|
Proteinuria |
Mesangial proliferative lesion
(8.3%) |
Hematuria |
Diffuse proliferative lesion
(8.3%) |
AKI |
Amyloidosis (5%) |
Jayalakshmi
(1987)2525. Jayalakshmi P, Looi LM, Lim KJ, Rajogopalan K. Autopsy findings
in 35 cases of leprosy in Malaysia. Int J Lepr Other Mycobact Dis.
1987;55:510-4.
|
35 |
74 |
|
AKI |
Interstitial nephritis |
Amyloidosis |
Al-Mohaya (1988)22. Al-Mohaya SA, Coode PE, Alkhder AA, Al-Suhaibani MO. Renal
granuloma and mesangial proliferative glomerulonephritis in leprosy. Int J Lepr
Other Mycobact Dis. 1988;56:599-602.
|
1 |
17 |
M |
Proteinuria |
Membranoproliferative nephropathy |
Madiwale (1994)3434. Madiwale CV, Mittal BV, Dixit M, Acharya VN. Acute renal failure
due to crescentic glomerulonephritis complicating leprosy. Nephrol Dial
Transplant. 1994;9:178-9.
|
2 |
30-45 |
M |
Proteinuria |
Crescentic nephropathy |
Hematuria |
Ahsan (1995)11. Ahsan N, Wheeler DE, Palmer BF. Leprosy-associated renal disease:
case report and review of the literature. J Am Soc Nephrol.
1995;5:1546-52.
|
1 |
79 |
M |
Hematuria |
Diffuse proliferative lesion |
AKI |
Lau (1995)3131. Lau G. A fatal case of drug-induced multi-organ damage in a
patient with Hansen's disease: dapsone syndrome or rifampicin toxicity?
Forensic Sci Int. 1995;73:109-15.
|
1 |
71 |
M |
AKI |
Interstitial nephritis |
Drug hepatitis |
Nakayama (2001)3838. Nakayama EE, Ura S, Fleury RN, Soares V. Renal lesions in
leprosy: a retrospective study of 199 autopsies. Am J Kidney Dis.
2001;38:26-30.
|
199 |
47-74 |
M (79.3%) |
|
Amyloidosis (31%) |
Diffuse proliferative lesion
(5%); |
Focal proliferative (4%); |
Membranoproliferative (2%); |
Membranous (1%); |
Mesangial proliferative lesion
(0.5%) |
Glomerular sclerosis (11%) |
Tubulo-interstitial nephritis
(9%) |
Granulomata (1%) |
Oliveira (2008)4040. Oliveira RA, Silva GB Jr, Souza CJ, Vieira EF, Mota RM, Martins
AM, et al. Evaluation of renal function in leprosy: a study of 59 consecutive
patients. Nephrol Dial Transplant. 2008; 23:256-62.
|
59 |
43 ± 15 |
M (51%) |
Concentration defect (84%) |
No |
Acidification defect (30%) |
Function loss (50%) |
Sharma (2010)4949. Sharma A, Gupta R, Khaira A, Gupta A, Tiwari SC, Dinda AK. Renal
involvement in leprosy: report of progression from diffuse proliferative to
crescentic glomerulonephritis. Clin Exp Nephrol.
2010;14:268-71.
|
1 |
25 |
F |
AKI |
Crescentic nephropathy |
Proteinuria |
Silva Junior (2010)5252. Silva Junior GB, Barbosa OA, Barros RM, Carvalho P dos R,
Mendoza TR, Barreto DM, et al. Amiloídose e insuficiência renal
crônica terminal associada à hanseníase. Rev Soc Bras Med Trop.
2010;43:474-6.
|
1 |
58 |
M |
CKD |
AA Amyloidosis |
Daher (2011)1010. Daher EF, Silva GB Jr, Cezar LC, Lima RS, Gurjão NH, Mota
RM, et al. Renal dysfunction in leprosy: a historical cohort of 923 patients in
Brazil. Trop Doct. 2011;41:148-50.
|
923 |
41 ± 19 |
M (53.3%) |
Proteinuria (4.8%) |
No |
Hematuria (6.8%) |
Function loss (3.8%) |