The aim of this study was to evaluate the effects of dengue virus infection during pregnancy and its correlation with low birth weight, prematurity, and asphyxia. A non-concurrent cohort study reveals the association of dengue during pregnancy with prematurity and low birth weight, when birth occurred during the maternal-fetal viremia period (p = 0.016 and p < 0.0001, respectively).
Dengue; Pregnancy; Newborn; Prematurity; Low birth weight
| Mother/Neonate | Neonate's gestational age | Total (%) | |
|---|---|---|---|
| < 37 weeks (%) | >= 37 weeks (%) | ||
| Mother with dengue and neonate born within the MFVP | 6 (14.6) | 35 (85.4) | 41 (100.0) |
| Mother with dengue and neonate Born outside MFVP | 14 (4.7) | 281 (95.3) | 295 (100.0) |
| Mother without dengue | 17,079 (4.9) | 328.520 (95.1) | 345,599 (100.0) |
| Total | 17,099 (4.9) | 328.836 (95.1) | 345,935 (100.0) |
| Mother/Neonate | Low birth weight | Total (%) | |
|---|---|---|---|
| Yes (%) | No (%) | ||
| Mother with dengue and neonate born within MFVP | 9 (22.0) | 32 (78.0) | 41 (100.0) |
| Mother with dengue and neonate born outside the MFVP | 13 (4.4) | 282 (95.6) | 295 (100.0) |
| Mother without dengue | 18,017 (5.2) | 327,582 (94.8) | 345,599 (100.0) |
| Total | 17,099 (4.9) | 328,836 (95.1) | 345,935 (100.0) |
