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Revista do Instituto de Medicina Tropical de São Paulo

On-line version ISSN 1678-9946


EYER-SILVA, Walter de Araujo et al. Secondary syphilis presenting as a corymbiform syphilide: case report and review. Rev. Inst. Med. trop. S. Paulo [online]. 2018, vol.60, e40.  Epub Aug 20, 2018. ISSN 1678-9946.

It is essential that healthcare providers are familiar with the full spectrum of clinical presentations of syphilis. A rare manifestation of secondary syphilis is the corymbiform (or corymbose) arrangement, in which a central greater papule is surrounded by smaller satellite lesions. Very few reports of corymbiform syphilis are available in current biomedical databases. We present the case of a 28 year-old HIV-infected male patient on regular, successful antiretroviral therapy who developed an asymptomatic corymbiform maculopapular lesion in the medial aspect of the right thigh. There were also a few brownish macular lesions on the left sole. New serological tests for syphilis (which had been negative in the past) were reactive. The coymbiform lesion slowly regressed and the non-treponemal test reverted to negative after benzathine penicillin G treatment. A review of the literature is provided. This is the first report of corymbiform syphilis in an HIV-infected patient.

Keywords : Corymbiform; Corymbose; HIV infection; Syphilis.

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