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Revista da Sociedade Brasileira de Medicina Tropical

Print version ISSN 0037-8682

Abstract

PINHEIRO, Maria da Conceição Nascimento et al. Análise quantitativa de mastócitos e de granulócitos eosinófilos no miocárdio de ratos wistar cronicamente infectados pelo Trypanosoma cruzi. Contribuição ao conhecimento da fibrose miocárdia. Rev. Soc. Bras. Med. Trop. [online]. 1992, vol.25, n.1, pp.45-50. ISSN 0037-8682.  http://dx.doi.org/10.1590/S0037-86821992000100007.

We did mast cell and eosinophil granulocyte counts in the myocardium of forty chronic chagasic Wistar albino rats. We used 10 controls rats and 30 animals with late stage (8th month) infection of São Felipe, Y and Colombian Trypanosoma cruzi strains, with variable degree of chronic myocarditis. We found chronic fibrosing myocarditis (fibrosis) in 40% of the infected animals. It was detected increased mast cell count in the chagasic rats associated with infection and not related with myocardial fibrosis. There was no increase in the eosinophil counts.

Keywords : Chagas'disease; Myocardial fibrosis; Mast cell; Eosinophil granulocyte.

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