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Revista da Sociedade Brasileira de Medicina Tropical
On-line version ISSN 1678-9849
SILVESTRE, Marco Túlio Alvarenga et al. Monoartrite de joelho como manifestação isolada de paracoccidiodomicose. Rev. Soc. Bras. Med. Trop. [online]. 1997, vol.30, n.5, pp. 393-395. ISSN 1678-9849. http://dx.doi.org/10.1590/S0037-86821997000500008.
Osteoarthritis in paracoccidioidomycosis has been rarely reported. The present case describes a 36 "year"old woman, with chronic monoarthritis in the knee lasting 4 years. The diagnosis was achieved only after sinovial biopsy, by anatomopathological examination showing granulomatous reaction with a large number of the characteristic "pilot wheel" Paracoccidioides brasiliensis yeast cells. Specific therapy, initially with ketoconazole and followed by cotrimoxazole led to complete functional recovery of the compromised joint. No other affected site was detected by various propaedeutic methods, including computed axial tomography of the thorax and abdomen. The authors emphasize the rarity of the case and discuss its possible pathophysiology.
Keywords : Arthritis; Knee; Paracoccidioidomycosis; Paracoccidioides brasiliensis.