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Description of a possible clonal expansion of Plasmodium vivax in Manaus - Amazonas - Brazil

Descrição de uma possível expansão clonal do Plasmodium vivax em Manaus - Amazonas - Brasil

Atypical P. vivax cases reported in Manaus municipality led us to detect a genetic isolate of P. vivax. Variable regions of SSUrRNA were examined from the initial time of infection and in the two recrudescences/relapses from a patient exhibiting chloroquine and primaquine resistance. A unique isolate, found at all stages of infection, suggests the presence of a clonal expansion.

P. vivax; Clonal expansion; Resistance


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