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Aplastic crisis caused by parvovirus B19 in an adult patient with sickle-cell disease

Crise aplástica por parvovírus B19 em um paciente adulto com doença falciforme

We describe a case of aplastic crisis caused by parvovirus B19 in an adult sickle-cell patient presenting with paleness, tiredness, fainting and dyspnea. The absence of reticulocytes lead to the diagnosis. Anti-B19 IgM and IgG were detected. Reticulocytopenia in patients with hereditary hemolytic anemia suggests B19 infection.

Human parvovirus B19; Sickle-cell disease; Transient aplastic crisis; Reticulocytopenia


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