SciELO - Scientific Electronic Library Online

 
vol.35 issue6Developmental characteristics of Cysticercus cellulosae in the human brain and heartPredictors of an unsatisfactory response to pentavalent antimony in the treatment of American visceral leishmaniasis author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Revista da Sociedade Brasileira de Medicina Tropical

Print version ISSN 0037-8682

Abstract

PASSOS, Xisto Sena et al. Antifungal activity of Caryocar brasiliensis (Caryocaraceae) against Cryptococcus neoformans. Rev. Soc. Bras. Med. Trop. [online]. 2002, vol.35, n.6, pp. 623-627. ISSN 0037-8682.  http://dx.doi.org/10.1590/S0037-86822002000600013.

The widespread occurrence of cryptococcosis mainly in immunocompromised patients and the side effects of available drugs which are effective against this mycosis have led investigators to search for new antimycotic agents. Caryocar brasiliensis derived compounds were investigated against Cryptococcus neoformans using the agar dilution method. Based on MIC values, the best results were obtained with a concentration of < 250µg/mL of cuticular waxes of the Caryocar brasiliensis leaf collected during the dry period (170.8mm of precipitation) which inhibited the growth of 91.3% (21/23) Cryptococcus neoformans isolates.

Keywords : Caryocar brasiliensis; Cerrado plant; Cryptococcus neoformans; Antifungal activity.

        · abstract in Portuguese     · text in Portuguese     · pdf in Portuguese