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Revista da Sociedade Brasileira de Medicina Tropical
On-line version ISSN 1678-9849
PEREIRA, Valéria Rêgo Alves et al. Hematological and histopathological evaluation of BALB/c and C57BL/6 mice exposed to Cytoplasmic Repetitive Antigen and Flagellar Repetitive Antigen recombinant antigens of Trypanosoma cruzi. Rev. Soc. Bras. Med. Trop. [online]. 2003, vol.36, n.6, pp. 739-742. ISSN 1678-9849. http://dx.doi.org/10.1590/S0037-86822003000600016.
The Cytoplasmic Repetitive Antigen and Flagellar Repetitive Antigen recombinant antigens of Trypanosoma cruzi were inoculated into BALB/c and C57BL/6 mice and its effects evaluated at hematological and histopathological levels. The results showed that the histological pattern of the organs and the hematological profile of mice were not modified suggesting that these antigens are not harmful for the animal.
Keywords : Trypanosoma cruzi; Recombinant antigens; Hematological and histological profiles.