SciELO - Scientific Electronic Library Online

vol.39 issue6Molecular diagnosis of the natural infection rate due to Leishmania sp in sandflies (Psychodidae, Lutzomyia) in the Amazon region of Maranhão, BrazilHTLV-1 and HTLV-2 proviral load: a simple method using quantitative real-time PCR author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Revista da Sociedade Brasileira de Medicina Tropical

On-line version ISSN 1678-9849


UEHARA, Patrícia Moreira; CUNHA, Rivaldo Venâncio da; PEREIRA, Gracy Regina Oliveira L.  and  OLIVEIRA, Priscilla Alexandrino de. Liver involvement in patients with dengue hemorrhagic fever: a rare phenomenon?. Rev. Soc. Bras. Med. Trop. [online]. 2006, vol.39, n.6, pp. 544-547. ISSN 1678-9849.

Hepatic manifestations are described as unusual complications of dengue and may lead to severe and potentially lethal conditions. Liver abnormalities in 41 patients diagnosed with dengue hemorrhagic fever in Campo Grande, Mato Grosso do Sul, Brazil, between January 1 and March 31, 2002, were evaluated. All were serologically positive for dengue in laboratory tests (IgM ELISA). ALT alterations were observed in 61% (25/41) and AST alterations in 80.5% (33/41), but there were no statistically significant differences between the various clinical forms. The range in ALT levels was 14-547U/l and in AST levels was 11-298U/l. Nausea and/or vomiting were reported by 90% (37/41) of the patients; 46.3% (19/41) had abdominal pain and 10% (3/29) presented hepatomegaly at clinical examination. The patients' ages ranged from 18 to 88 years; 23 (56%) were female and 18 (44%) were male.

Keywords : Dengue; Dengue hemorrhagic fever; Hepatic alterations; Mato Grosso do Sul State; Brazil.

        · abstract in Portuguese     · text in Portuguese     · Portuguese ( pdf epdf )


Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License