Abstract

RETAMOZO-PALACIOS, Manuel; SOUSA, João Batista de  and  SANTOS, João Barberino. Anorrectal lesions in HIV-positive patients using highly active antiretroviral therapy. Rev. Soc. Bras. Med. Trop. [online]. 2007, vol.40, n.3, pp. 286-289. ISSN 0037-8682.  http://dx.doi.org/10.1590/S0037-86822007000300007.

Anorectal lesions are common in patients with human immunodeficiency virus (HIV). Highly active anti-retroviral therapy (HAART) has little influence on the progression of anal neoplasms. The prevalence of anorectal lesions in 88 HIV-positive patients attended at the infectious diseases service of the University Hospital of Brasília who were using HAART was studied. Sociodemographic data were collected using a pre-prepared questionnaire and then the patients underwent proctological examination. Around 71% of the patients said they practiced anal intercourse. 30.7% were using a protease inhibitor. The prevalence of anorectal lesions was 36.4%, and condyloma acuminata and anal fissure were the most frequent of these. Condyloma acuminata was the most prevalent anorectal lesion and was strongly associated with the use of lopinavir/ritonavir. Screening for anorectal lesions caused by human papillomavirus in HIV/AIDS patients who use protease inhibitors is suggested.

Keywords : HIV; AIDS; Anorectal lesions; HAART.