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Revista da Sociedade Brasileira de Medicina Tropical

versión impresa ISSN 0037-8682versión On-line ISSN 1678-9849

Resumen

SANTOS, Carolina Cincurá Silva; ONOFRE-NUNES, Záira  y  ANDRADE, Zilton Araujo. Role of partial hepatectomy on Capillaria hepatica-induced hepatic fibrosis in rats. Rev. Soc. Bras. Med. Trop. [online]. 2007, vol.40, n.5, pp.495-498. ISSN 0037-8682.  http://dx.doi.org/10.1590/S0037-86822007000500001.

It is known that hepatic fibrosis may regress following partial hepatectomy, since the hepatic parenchyma regenerates very rapidly, but not the excess of fibrous tissue. The present study evaluated this hypothesis by observing the behavior of systematized septal fibrosis induced by either 30 or 90-day-old Capillaria hepatica infection, in rats subjected to partial hepatectomy. The results revealed that the morphology of the fibrosis was unaffected, but its relative quantity within the microscope field appeared significantly decreased, as a consequence of the increased liver tissue mass following regeneration.

Palabras clave : Hepatectomy; Fibrosis; Capillaria hepatica.

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