Revista da Sociedade Brasileira de Medicina Tropical
Print version ISSN 0037-8682
PRUDENTE, Mariana Félix de Souza; LIMA, Kelly Cristine and CARVALHAES, Mara Silvia. Hematological, serum biochemical and serological profile of Felis domesticus with experimental lagochilascariosis. Rev. Soc. Bras. Med. Trop. [online]. 2008, vol.41, n.5, pp. 496-501. ISSN 0037-8682. http://dx.doi.org/10.1590/S0037-86822008000500012.
The present study evaluated the hemogram, different proteins, plasma enzymes, serum enzymes and specific antibody production of Felis domesticus experimentally infected by Lagochilascaris minor. The infected animals were seen to present increased total leukocytes (particularly eosinophils), decreased platelet counts, increased aspartate-aminotransferase and alanine-aminotransferase and, especially, the presence of specific IgG antibodies against antigens of the parasite. The reaction with crude extract of adult parasites was shown to be more specific, thereby enabling serum discrimination between the animals: non-infected, infected with other parasites and infected with lagochilascariosis. This is the first description of the standardization of a serological reaction for diagnosing lagochilascariosis in Felis domesticus.
Keywords : Lagochilascaris minor; Lagochilascariosis; Hemogram; Biochemical tests; Antibodies.