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Revista da Sociedade Brasileira de Medicina Tropical
Print version ISSN 0037-8682
On-line version ISSN 1678-9849
DIAS, João Carlos Pinto et al. Further evidence of spontaneous cure in human Chagas disease. Rev. Soc. Bras. Med. Trop. [online]. 2008, vol.41, n.5, pp.505-506. ISSN 0037-8682. http://dx.doi.org/10.1590/S0037-86822008000500014.
An acute case of Chagas disease was studied in 1944, with clinical and laboratory follow-up until 2007, in Bambuí, Minas Gerais, Brazil. A five-year-old girl living in a rural hut that was highly infested with Triatoma infestans presented a febrile clinical condition compatible with the acute form of trypanosomiasis. She presented a positive thick blood smear, but never again showed serological and/or parasitological evidence of Trypanosoma cruzi infection, on several occasions. This patient never received any specific treatment and, to this day, she remains completely asymptomatic, with normal findings from clinical, electrocardiographic, X-ray and echocardiographic examinations.
Keywords : Chagas disease; Spontaneous cure; Longitudinal study.