Revista da Sociedade Brasileira de Medicina Tropical
Print version ISSN 0037-8682
MACEDO, Rafael Nogueira et al. Severe coinfection of melioidosis and dengue fever in northeastern Brazil: first case report. Rev. Soc. Bras. Med. Trop. [online]. 2012, vol.45, n.1, pp. 132-133. ISSN 0037-8682. http://dx.doi.org/10.1590/S0037-86822012000100028.
This report focuses on a fatality involving severe dengue fever and melioidosis in a 28-year-old truck driver residing in Pacoti in northeastern Brazil. He exhibited long-term respiratory symptoms (48 days) and went through a wide-ranging clinical investigation at three hospitals, after initial clinical diagnoses of pneumonia, visceral leishmaniasis, tuberculosis, and fungal sepsis. After death, Burkholderia pseudomallei was isolated in a culture of ascitic fluid. Dengue virus type 1 was detected by polymerase chain reaction in cerebrospinal fluid (CSF); this infection was the cause of death. This description reinforces the need to consider melioidosis among the reported differential diagnoses of community-acquired infections where both melioidosis and dengue fever are endemic.
Keywords : Melioidosis; Dengue fever; Coinfection.