SciELO - Scientific Electronic Library Online

vol.45 issue2Comparison among three polymerase chain reaction assays on detection of DNA from Leishmania in biological samples from patients with american cutaneous leishmaniasisPatient with chronic Chagas heart disease, hepatosplenic schistosomiasis and acquired immunodeficency syndrome: possible spontaneous resolution of thrombus in the right ventricle author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




Related links


Revista da Sociedade Brasileira de Medicina Tropical

Print version ISSN 0037-8682


FAGUNDES, Glauco Danielle; TABALIPA, Fábio de Oliveira  and  SILVA, Jane da. Antibody levels in children after 10 years of vaccination against hepatitis B: a brazilian community-based study. Rev. Soc. Bras. Med. Trop. [online]. 2012, vol.45, n.2, pp.260-262. ISSN 0037-8682.

INTRODUCTION: It is known that the hepatitis B (HB) vaccine is effective, but it is alarming that sudden drops of antibody levels may coincide with the onset of adolescence. METHODS: Antibody levels against HB vaccine surface antigen (anti-HBs) and HB vaccine core antigen (anti-HBc) were measured on the blood samples of children with a mean age of 11.4 years. RESULTS: About 54.8% had protective levels of anti-HBs. Of those who were anti-HBc-positive (4.4%), an average of 218.4 anti-HBs mIU/mL was found. CONCLUSIONS: Immunological protection was found in the majority of children. However, more studies are needed to elucidate the heritability of nonresponders and establish strategies against such events.

Keywords : Hepatitis B virus; Vaccination; Anti-HBs; Anti-HBc; HBsAg.

        · abstract in Portuguese     · text in English     · English ( pdf )


Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License