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Revista da Sociedade Brasileira de Medicina Tropical
versión impresa ISSN 0037-8682
BASTOS, Michele de Souza et al. Simultaneous circulation of all four dengue serotypes in Manaus, State of Amazonas, Brazil in 2011. Rev. Soc. Bras. Med. Trop. [online]. 2012, vol.45, n.3, pp. 393-394. ISSN 0037-8682. http://dx.doi.org/10.1590/S0037-86822012000300022.
INTRODUCTION: Manaus, the capital city of the state of Amazon with nearly 2 million inhabitants, is located in the middle of the Amazon rain forest and has suffered dengue outbreaks since 1998. METHODS: In this study, blood samples were investigated using reverse transcriptase-polymerase chain reaction (RT-PCR), aimed at identifying dengue virus serotypes. RESULTS: Acute phase sera from 432 patients were tested for the presence of dengue virus. Out of the 432 patients, 137 (31.3%) were found to be positive. All the four dengue virus serotypes were observed. CONCLUSIONS: The simultaneous circulation of the four dengue serotypes is described for the first time in Manaus and in Brazil.
Palabras clave : Dengue; Reverse transcriptase-polymerase chain reaction; Serotypes.