Resumo

BERNARDES FILHO, Fred et al. HAART: a risk factor for development of porphyria cutanea tarda?. Rev. Soc. Bras. Med. Trop. [online]. 2012, vol.45, n.6, pp.764-767. ISSN 0037-8682.  https://doi.org/10.1590/S0037-86822012000600022.

Porphyria cutanea tarda (PCT) is caused by inherited or acquired partial deficiency of the uroporphyrinogen-decarboxylase (Uro-D) enzyme activity. It is the most common form of porphyria. The main triggering factors to the development of porphyria cutanea tarda are alcohol, hepatitis C virus and human immunodeficiency virus. There are several reports of PCT associated with drugs, among them, antiretroviral therapy. We describe three HIV-positive patients, which showed photosensitivity as well as the emergence of tense blisters on sun-exposed areas during the use of highly active antiretroviral therapy (HAART) and discuss the possibility of PCT after the use of these drugs by those patients.

Palavras-chave : Porphyria cutanea tarda; HAART; HIV.

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