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Revista da Sociedade Brasileira de Medicina Tropical

Print version ISSN 0037-8682

Abstract

SILVA, Cecília Rocha da; MAGALHAES, Hemerson Iury Ferreira; MORAES, Manoel Odorico de  and  NOBRE JUNIOR, Hélio Vitoriano. Susceptibility to amphotericin B of Candida spp. strains isolated in Ceará, Northeastern Brazil. Rev. Soc. Bras. Med. Trop. [online]. 2013, vol.46, n.2, pp.244-245. ISSN 0037-8682.  http://dx.doi.org/10.1590/0037-8682-1060-2013.

Introduction

Amphotericin B (AMB) is an antifungal agent used extensively in clinical medicine, yet resistance remains low. This study aims to evaluate the susceptibility of Candida spp. against AMB.

Methods

For broth microdilution susceptibility testing, 77 strains of Candida spp. were selected (32 C. albicans, 33 C. tropicalis, and 12 C. parapsilosis). The strains were considered susceptible when they exhibited MIC≤1.0µg/ml.

Results

None of the strains showed an MIC greater than 0.25µg/ml.

Conclusions

Further works are necessary, with a higher number of strains, to assess the validity of the results used in this study.

Keywords : Amphotericin B; Candida spp; Protocol M27-A3.

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