Introduction
The role of trypanocidal therapy in the chronic phase of Chagas disease remains controversial.
Methods
A total of 13 patients with chronic Chagas disease were treated with benznidazole (5mg/kg/day/60 days) and surveyed via antibody measurement and conventional electrocardiogram over the course of 4 years.
Results
The antibody titers were significantly reduced after 4 years (p<0.05). Most of the patients showed maintenance of the initial clinical picture (electrocardiographic), with the exception of 4 cases.
Conclusions
Although trypanocidal therapy in the chronic phase of Chagas disease was of limited effectiveness, we believe that it is beneficial in treating these patients.
Benznidazole; Chagas disease; Pharmacotherapy follow-up
