ABSTRACT
INTRODUCTION:
In this study, the molecular characteristics of group A rotavirus (RVA) were compared in samples obtained before and after RVA vaccine-introduction in Brazil.
METHODS:
Eighty samples were screened for the presence of RVA. Positive samples were molecularly analyzed.
RESULTS:
RVA positivity was 16.9%, with a predominance of G2P[4]. Periods: pre-vaccination: predominance of IId (G1), IId (G2) lineages, and I1 and E1 genotypes; post-vaccination: predominance of Ib (G1), IIa, and IIc (G2) lineages and I2 and E2 genotypes.
CONCLUSIONS:
Although changes in RVA-circulation pattern were observed in the post-vaccination period, it could not be attributed to vaccination process.
Keywords:
Rotavirus A; Gastroenteritis; Vaccine
