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Short Communications • Rev. Soc. Bras. Med. Trop. 49 (06) • Nov-Dec 2016 • https://doi.org/10.1590/0037-8682-0078-2016   copy

High incidence of hypertriglyceridemia in a Brazilian cohort of people living with HIV/AIDS undergoing antiretroviral treatment in Belo Horizonte, 2001-2010

Authorship SCIMAGO INSTITUTIONS RANKINGS

Abstract

INTRODUCTION:

Hypertriglyceridemia incidence should be estimated in HIV-infected patients after antiretroviral therapy (ART) initiation.

METHODS:

We retrospectively analyzed clinical data of HIV-infected adults at 3 public referral centers. Cumulative and person-time incidences were estimated for patients without hypertriglyceridemia. Survival time and hazard ratio (HR) were estimated by Kaplan-Meier analysis and Cox proportional regression, respectively.

RESULTS:

Cumulative and person-time incidences were 40.4% and 1.4 cases/100 person-months, respectively. The median period for hypertriglyceridemia occurrence was 47 months. Men and patients with switched ART regimens had increased hypertriglyceridemia risk (HR=3.05 and 3.34, respectively).

CONCLUSIONS:

Hypertriglyceridemia incidence is high in HIV-infected patients undergoing ART.

Keywords:
HIV/AIDS; Hypertriglyceridemia; ART

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