Cohort studies |
|
|
|
|
|
Pereira et al, 19851818. Pereira JB, Willcox HP, Coura JR. Morbidity in Chagas' disease. III. Longitudinal study of 6 years, in Virgem da Lapa, MG, Brazil. Mem Inst Oswaldo Cruz . 1985;80(1):63-71.
|
248 |
ChD vs Seronegatives |
Progression to HF |
6 years |
EI, VR, VES incidence |
Acquatella et al, 19875555. Acquatella H, Catalioti F, Gomez-Mancebo JR, Davalos V, Villalobos L. Long-term control of Chagas disease in Venezuela: effects on serologic findings, electrocardiographic abnormalities, and clinical outcome. Circulation. 1987;76(3):556-62.
|
775 |
With and without cardiomyopathy |
Functional class (NYHA) |
5 years |
Abnormal ECG |
Barretto et al, 19892727. Barretto AC, Bellotti G, Deperon SD, Arteaga-Fernandez E, Mady C, Ianni BM, et al. The value of the electrocardiogram in evaluating myocardial function in patients with Chagas' disease. Arq Bras Cardiol . 1989;52(2):69-73.
|
1,004 |
ChD |
Functional class (NYHA), cardiothoracic index |
2 years |
Higher incidence of abnormal ECG in NYHA III and IV. |
Ianni et al, 200155. Ianni BM, Arteaga E, Frimm CC, Pereira Barretto AC, Mady C. Chagas' heart disease: evolutive evaluation of electrocardiographic and echocardiographic parameters in patients with the indeterminate form. Arq Bras Cardiol. 2001;77(1):59-62.
|
159 |
ChD indeterminate form |
LVEF |
98.6+/- 30.4 months |
Incidence of new ECG alterations had no impact on LVEF |
Nascimento et al, 20123333. Nascimento BR, Araujo CG, Rocha MO, Domingues JD, Rodrigues AB, Barros MV, et al. The prognostic significance of electrocardiographic changes in Chagas disease. J Electrocardiol. 2012;45(1):43-8.
|
152 |
With and without cardiomyopathy |
Drop of 5% of LVEF, diameter of the left ventricle in diastole |
6.8 years |
QRS duration and appearance of new ECG alterations. |
Cross-sectional studies |
|
|
|
|
|
Casado et al., 19903434. Casado J, Davila DF, Donis JH, Torres A, Payares A, Colmenares R, et al. Electrocardiographic abnormalities and left ventricular systolic function in Chagas' heart disease. Int J Cardiol . 1990;27(1):55-62.
|
44 |
ChCM without HF |
LVEF, left ventricle volume |
Cross-sectional |
Association of ECG alterations in the same tracing. |
Ribeiro et al., 20003232. Ribeiro AL, Rocha MO, Barros MV, Rodrigues AR, Machado FS. A narrow QRS does not predict a normal left ventricular function in Chagas' disease. Pacing Clin Electrophysiol. 2000;23(11 Pt 2): 2014-7.
|
98 |
With and without cardiomyopathy |
LVEF, Diameter of the left ventricle in diastole |
Cross-sectional |
QRS > 100ms. |
Salles et al., 20035656. Salles GF, Cardoso CR, Xavier SS, Sousa AS, Hasslocher-Moreno A. Electrocardiographic ventricular repolarization parameters in chronic Chagas' disease as predictors of asymptomatic left ventricular systolic dysfunction. Pacing Clin Electrophysiol . 2003;26(6):1326-35.
|
738 |
With and without cardiomyopathy |
LVEF |
Cross-sectional |
QTd > 60ms, VES > 10%, LBBB |
Marques et al., 20062525. Marques DS, Canesin MF, Barutta Jr F, Fuganti CJ, Barretto AC. Evaluation of asymptomatic patients with chronic Chagas disease through ambulatory electrocardiogram, echocardiogram and B-Type natriuretic peptide analyses. Arq Bras Cardiol . 2006;87(3):336-43.
|
106 |
Asymptomatic chronic ChD |
Diastolic and systolic dysfunction |
Cross-sectional |
Presence of typical ECG alterations |
Strauss et al., 20113535. Strauss DG, Cardoso S, Lima JA, Rochitte CE, Wu KC. ECG scar quantification correlates with cardiac magnetic resonance scar size and prognostic factors in Chagas' disease. Heart. 2011;97(5):357-61.
|
44 |
With and without cardiomyopathy |
Late gadolinium enhancement area, reduced LVEF |
Cross-sectional |
QRS score |
Ribeiro et al., 20131414. Ribeiro AL, Sabino EC, Marcolino MS, Salemi VM, Ianni BM, Fernandes F, et al. Electrocardiographic abnormalities in Trypanosoma cruzi seropositive and seronegative former blood donors. PLoS Negl Trop Dis. 2013;7(2):e2078.
|
1,000 |
With and without cardiomyopathy |
LVEF |
Cross-sectional |
QTc interval, QRS duration. |