The burden of hepatitis C infection in a Southern Brazilian State

An ecologic study was carried out to estimate the disability-adjusted life years (DALY) by summing the number of years of life lost and the number of years lived with disability.

RESULTS

A rate of 1,075.9 DALY/100,000 population was estimated, and was similar by sex. The highest burden was between the ages of 45 to 59 years and in the Grande Oeste region.

CONCLUSIONS

The burden of hepatitis C was high and concentrated in adult age groups with variations among regions.

Keywords:
Epidemiology; Hepatitis C; Impact; Burden of disease

Clinical condition	Cases		Weight	Duration
	n	%		(years)
Hepatocellular carcinoma	276	0.7	0.075	1.02
Mild/moderate hepatitis	30,412	76.5	0.075	25
Compensated cirrhosis	7,570	19.0	0.075	10
Decompensated cirrhosis	1,514	3.8	0.075	4.5
Total	39,772	100.0	-	-

Variables	YLD			YLL			DALYs
Variables	n	%	rate	n	%	rate	n	%	rate
Gender
female	30,667.56	48.5	996.0	500.4	19.2	16.5	31,168.0	47.3	1,012.2
male	32,564.53	51.5	1,071.3	2,100.0	80.8	69.1	34,664.6	52.7	1,140.4
Age groups (years)
< 1	386.9	0.6	497.7	-	-	-	386.9	0.6	497.7
1-4	663.3	1.0	195.3	-	-	-	663.3	1.0	195.3
5-14	2,128.0	3.4	215.5	29.0	1.1	5.8	2,157.0	3.3	432.0
15-29	15,020.4	23.7	920.3	-	-	-	15,020.4	22.8	1,364.9
30-44	21,528.8	34.0	1,549.5	421.0	16.2	30.5	21,949.8	33.3	1,592.8
45-59	17,106.9	27.0	1,615.3	1,396.0	53.7	130.4	18,502.9	28.1	1,728.5
60-69	4,380.4	6.9	1,211.1	502.3	19.3	138.9	4,882.7	7.4	1,350.0
70-79	1,395.6	2.2	732.6	252.0	9.7	132.3	1,647.7	2.5	864.9
≥ 80	621.8	0.9	764.4	-	-	-	621.8	0.9	764.4
Health macro-regions
Foz do Rio Itajaí	4,609.7	7.6	899.3	36.5	1.4	7.1	4,646.2	7.3	906.4
Grande Florianópolis	7,871.1	12.9	805.3	965.9	37.1	98.8	8,836.6	13.9	904.1
Grande Oeste	22,003.9	36.2	3,007.3	127.9	4.9	17.5	22,131.8	34.9	3,024.8
Meio Oeste	5,174.5	8.5	871.2	-	-	-	5,174.5	8.2	871.2
Nordeste	6,419.6	10.6	773.4	518.2	19.9	62.4	6,937.7	10.9	835.8
Planalto Norte	103.2	0.2	28.4	-	-	-	103.2	0.2	28.4
Serra Catarinense	261.2	0.4	86.5	-	-	-	261.2	0.4	86.5
Sul	9,887.5	16.3	1,105.7	952.4	36.6	106.5	10,839.9	17.1	1,212.2
Vale do Itajaí	4,403.2	7.2	482.1	-	-	-	4,403.2	6.9	482.1
Total	63,232.1	100.0	992.6	2,600.4	100.0	42.5	65,832.5	100.0	1,075.9

Sociedade Brasileira de Medicina Tropical - SBMT Caixa Postal 118, 38001-970 Uberaba MG Brazil, Tel.: +55 34 3318-5255 / +55 34 3318-5636/ +55 34 3318-5287, http://rsbmt.org.br/ - Uberaba - MG - Brazil
E-mail: rsbmt@uftm.edu.br

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[1] Corresponding author: Prof. Jefferson Traebert e-mail:jefferson.traebert@gmail.com