Abstract
INTRODUCTION:
Introducing new antibiotics to the clinic is critical.
METHODS:
We adapted a plate method described by Kawaguchi and coworkers in 20131 for detecting inhibitory airborne microorganisms.
RESULTS:
We obtained 51 microbial colonies antagonist to Chromobacterium violaceum, purified and retested them, and of these, 39 (76.5%) were confirmed. They comprised 24 bacteria, 13 fungi, and 2 yeasts. Among the fungi, eight (61.5%) produced active extracts. Among the bacterial, yeast, and fungal strains, 17 (44.7%) and 12 (31.6%) were active against Candida albicans and Candida parapsilosis, respectively.
CONCLUSIONS:
The proposed screening method is a rapid strategy for discovering potential antibiotic producers.
Keywords:
Candida sp; Chromobacterium violaceum; Quorum sensing; Antimicrobials