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Revista do Hospital das Clínicas

versão impressa ISSN 0041-8781


SANTOS, Vitorino Modesto dos et al. Widespread hematogenous metastases and Trousseau's syndrome in gastric adenocarcinoma. Rev. Hosp. Clin. [online]. 2001, vol.56, n.3, pp. 91-96. ISSN 0041-8781.

A case of widespread hematogenous metastases and Trousseau's syndrome is reported in a 40 year-old white housewife with gastric cancer, presenting subdural hematoma, ecchymoses, epistaxis, stomach and uterine bleeding. After undergoing hematoma drainage, she was unsuccessfully treated with platelets, red blood cells, plasma cryoprecipitate transfusions, and antibiotics. Necropsy disclosed gastric ring-signet adenocarcinoma invading the serous layer, with massive disseminated intravascular coagulation and systemic neoplastic embolism. Multiple old and recent hyaline (rich in fibrin and platelets) microthrombi, and tumor emboli were observed in the bone marrow, meninges, liver, lungs, kidneys, lymph nodes, adrenals, thyroid, heart, pancreas, and ovaries (Krukenberg tumor).

Palavras-chave : Trousseau's syndrome; Disseminated intravascular coagulation; Subdural hematoma; Gastric cancer; Krukenberg tumor.

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