Abstract

ABREU, Viviane Gomes da Costa et al. Chemical constituents from the stem of Brosimum potabile (Moraceae). Acta Amaz. [online]. 2010, vol.40, n.4, pp. 711-718. ISSN 0044-5967.  http://dx.doi.org/10.1590/S0044-59672010000400011.

Three coumarins, 5-methoxypsoralene, xanthyletin, and (-)-marmesin, have been isolated from the ethanolic extract of the stem of the Amazonian plant Brosimum potabile. The structures were determined on the basis of NMR analyses and by comparison with spectroscopic data in the literature. The analysis of the hexane fractions by GC-MS in EIMS mode suggested the presence of (1-methylpentyl)-benzene; α,α-dimethyl-4-(1-methylethyl)-benzenemethanol; 1-methyl-3,5-bis(1-methylethyl)-benzene; urs-12-ene; chola-5,22-dien-3β-ol; cholesta-4,6-dien-3β-ol; sitosteryl 9(Z)-octadecenoate; cholesta-5,22-dien-3β-ol; cholesta-4,6,22-trien-3-one; and cholesta-4,22-dien-3-one. NMR data of other hexane fractions indicated the presence of 3β-acetoxy-lup-12,20(29)-diene; 3β-acetoxy-olean-12-ene; 3β-acetoxy-urs-12-ene; and adian-5-ene. All these compounds are first described in B. potabile.

Keywords : Brosimum potabile; coumarins; pentacyclic triterpenes; structural characterization by NMR and GC/MS.