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Print version ISSN 0044-5967
CREMASCO, Marco Aurelio and BRAGA, Nazareno de Pina. Isomerization of essential oil of (Piper hispidinervium) C. DC to obtain isosafrole. Acta Amaz. [online]. 2010, vol.40, n.4, pp. 737-740. ISSN 0044-5967. http://dx.doi.org/10.1590/S0044-59672010000400014.
The Brazilian peppers present proprieties that can be used in fragrance and pharmaceutical industries, for example. One these pepper is long pepper (Piper hispidinervium C. DC.), who its essential oil is rich in safrole. Safrole is an important compound with application in several industries, such as pharmaceutics, cosmetics. After its chemical conversion, for example, it is possible to obtain heliotropin, a fixative agent for fragrances. The sequence to obtain the heliotropin is by safrole isomerization, that, initially, produce isosafrole. In this work, however, presents the synthesis of isosafrole directly from essential oil of Piper hispidinervium C. DC. In this case, the isomerization of essential oil was done getting 79,4 % of cis, trans-isosafrole mixture. The essential oil presented 86,4 % of safrole, resulting in 97,1 % yield to cis, trans-isosafrole.
Keywords : Piper hispidinervium; Essential oil; Safrole; Isosafrole; Isomerization.