SciELO - Scientific Electronic Library Online

 
vol.62 issue1Association of depression, levels of pain and lack of social support in patients admitted to general medical wardsAttentional components and executive functions in children with ADHD: data of a flexible neuropsychological battery author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand

Journal

Article

Indicators

Related links

Share


Jornal Brasileiro de Psiquiatria

Print version ISSN 0047-2085

Abstract

SILBERMAN, Cláudia Débora; RODRIGUES, Cláudia Soares; ENGELHARDT, Eliasz  and  LAKS, Jerson. The impact of depression on survival of Parkinson's disease patients: a five-year study. J. bras. psiquiatr. [online]. 2013, vol.62, n.1, pp.8-12. ISSN 0047-2085.  http://dx.doi.org/10.1590/S0047-20852013000100002.

OBJECTIVE: The aim of this study is to evaluate the survival rate in a cohort of Parkinson's disease patients with and without depression. METHODS: A total of 53 Parkinson's disease subjects were followed up from 2003-2008 and 21 were diagnosed as depressed. Mean time of follow up was 3.8 (SD 95% = 1.5) years for all the sample and there was no significant difference in mean time of follow up between depressed and nondepressed Parkinson's disease patients. Survival curves rates were fitted using the Kaplan-Meier method. In order to compare survival probabilities according to the selected covariables the Log-Rank test was used. Multivariate analysis with Cox regression was performed aiming at estimating the effect of predictive covariables on the survival. RESULTS: The cumulative global survival of this sample was 83% with nine deaths at the end of the study - five in the depressed and four in the nondepressed group, and 55.6% died in the first year of observation, and none died at the fourth and fifth year of follow up. CONCLUSION: Our finding point toward incremental death risk in depressed Parkinson's disease patients.

Keywords : Parkinson's disease; depression; mortality.

        · abstract in Portuguese     · text in English     · English ( pdf )

 

Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License