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Arquivos Brasileiros de Cardiologia

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MENEZES, Igor Alexandre Côrtes de et al. Resistance to activated protein C and ischemic arterial disease in a young man. Arq. Bras. Cardiol. [online]. 2010, vol.94, n.3, pp.e91-e93. ISSN 0066-782X.

The assessment of activated protein C resistance (APCR) caused by mutations in factor V (factor V Leiden) is an important risk factor for venous thromboembolism, of which role as the originator of arterial obstructions in situ is still a controversial subject. The clinical case of a young patient with history of coronariopathy, multiple cerebrovascular lesions and peripheral artery disease is reported. The diagnostic investigation showed APCR as the possible etiology.

Keywords : Thrombophilia; factor V; blood coagulation; protein C resistance; arterial occlusive diseases.

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